Scientists Identify Treatment of Glioblastoma Brain Tumor
Researchers say they have identified a protein -- tyrosine phosphatase receptor type Z, or PTPRZ, -- as a drug target for patients with glioblastoma. Glioblastoma has been classified by the World Health Organization as the highest grade glioma, a type of brain tumor that is difficult to treat with the median survival rate of patients with glioblastoma is 14 months. There has been a lack of effective treatment options has spurred researchers to look for other treatment options. The study also showed that the allosteric inhibitor of PTPRZ known as NAZ2329 suppressed stem cell-like properties in glioblastoma cells in cultures and tumor growth.
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